Anthracyclines Induce Calpain-dependent Titin Proteolysis and Necrosis in Cardiomyocytes
| Author(s) | Chee Chew Lim, Christian Zuppinger, Xinxin Guo, Gabriela M. Kuster, Michiel Helmes, Hans M. Eppenberger, Thomas M. Suter, Ronglih Liao, and Douglas B. Sawyer |
| Journal | J. Biol. Chem., 279 |
Method Extract | |
| ... ...measured by dual excitation (360 and 380 nm) of the fura-2-loaded cells, and emission fluorescence was recorded at 510 nm (IonOptix Inc.). The fluorescence ratio (F 360/F 380) and time constant (tau) of the calcium transient decay reflect the intracellular... ... | |
Our Ref: 1488