IonOptix Video Tutorials: IonWizard Experiment Design
ionoptix2020-08-03T20:08:16-05:00A video tutorial highlighting experiment design in IonWizard.
Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription.
ISC Webmaster2019-11-09T22:14:04-05:00Fang, C. X., Dong, F., Thomas, D. P., Ma, H., He, L., & Ren, J. (2008). American Journal of Physiology-Heart and Circulatory Physiology, 295(3)
Vessel System HyperSwitch Config
ISC Webmaster2019-11-11T11:20:29-05:00Go back to RESOURCES Overview: Vessel System HyperSwitch Config Download
Replacing Your Xe Bulb
ISC Webmaster2019-10-21T19:44:21-05:00A brief guide to properly replacing your Xenon bulb with plenty of helpful pictures.
Myocyte Calcium & Contractility Recording System (HyperSwitch Configuration)
ISC Webmaster2019-10-22T15:54:02-05:00Complete real-time, turnkey system for calcium and contractility recording
HyperSwitch Hardware Manual
ISC Webmaster2019-10-21T19:29:36-05:00Go back to RESOURCES HyperSwitch Hardware Manual Download
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.
ionoptix2019-11-09T22:16:04-05:00Raake, P. W., Vinge, L. E., Gao, E., Boucher, M., Rengo, G., Chen, X., DeGeorge Jr., B.R., Matkovich, S., Houser, S.R., Most, P., Eckhart, A.D., Dornll, G.W., and Koch, W. J. (2008). Circulation Research, 103(4), 413-422
Glucocorticoid- and protein kinase A-dependent transcriptome regulation in airway smooth muscle.
ionoptix2019-11-09T22:20:21-05:00Misior, A. M., Deshpande, D. A., Loza, M. J., Pascual, R. M., Hipp, J. D., & Penn, R. B. (2009). American Journal of Respiratory Cell and Molecular Biology, 41(1), 24-39
Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle.
ionoptix2019-10-21T19:35:24-05:00Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle. Kramerova I, Kudryashova E, Wu B, Ottenheijm C, Granzier H, Spencer MJ Abstract: Calpain-3 (CAPN3) is a non-lysosomal cysteine protease that is necessary for normal muscle function, as mutations in CAPN3 result in an autosomal recessive form of limb girdle muscular dystrophy type 2A. To elucidate the biological roles of CAPN3 in skeletal muscle, we [...]
Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries.
ionoptix2019-10-22T18:25:49-05:00Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries. Zhao G, Adebiyi A, Blaskova E, Xi Q, Jaggar JH Abstract: Inositol 1, 4, 5-trisphosphate receptors (IP3Rs) regulate diverse physiological functions, including contraction and proliferation. Three IP3R isoforms exist, but functional significance of these subtypes in arterial smooth muscle cells is unclear. Here, we investigated relative expression and physiological functions of IP3R isoforms in [...]