Techniques and Best Practices for Cardiomyocyte Isolation
ionoptix2026-02-17T20:01:53-05:00Ronglih Liao and Davor Pavlovic discuss techniques for isolating myocytes using both traditional and Langendorff-free methodologies.
High-fat Diet-induced Obesity Leads to Resistance to Leptin-induced Cardiomyocyte Contractile Response.
ionoptix2019-10-22T17:39:59-05:00High-fat Diet-induced Obesity Leads to Resistance to Leptin-induced Cardiomyocyte Contractile Response. Jun Ren, Bang-Hao Zhu, David P. Relling, Lucy B. Esberg, Asli F. Ceylan-Isik Abstract: Levels of the obese gene product leptin are often elevated in obesity and may contribute to obesity-induced cardiovascular complications. However, the role of leptin in obesity-associated cardiac abnormalities has not been clearly defined. This study was designed to determine the influence of high-fat diet-induced obesity [...]
Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T.
ionoptix2019-10-22T20:06:59-05:00Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T. Lu XY, Chen L, Cai XL, Yang HT Abstract: Aims: Heat shock protein 27 (Hsp27) renders cardioprotection from ischaemia/reperfusion (I/R) injury, but little is known about its role in myofilaments. We proposed that increased expression of Hsp27 may improve post-ischaemic contractile dysfunction by preventing I/R-induced cardiac troponin I (cTnI) and troponin T [...]
Pim-1 Kinase Antagonizes Aspects Of Myocardial Hypertrophy And Compensation To Pathological Pressure Overload.
ISC Webmaster2019-11-09T22:23:45-05:00Muraski JA, Fischer KM, Wu W, Cottage CT, Quijada P, Mason M, Din S, Gude N, Alvarez R Jr, Rota M, Kajstura J, Wang Z, Schaefer E, Chen X, MacDonnel S, Magnuson N, Houser SR, Anversa P, Sussman MA
Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia
ionoptix2019-11-09T22:25:14-05:00Moshal, K. S., Tipparaju, S.M., Vacek, T. P., Kumar, M., Singh, M., Frank, I.E., Patibandla, P.K., Tyagi, N., Rai, J., Metreveli, N., Rodriguez, W.E., Tseng, M.T., and Tyagi, S.C. American Journal of Physiology-Heart and Circulatory Physiology,295(2)
Leptin Attenuates Cardiac Contraction In Rat Ventricular Myocytes. Role of NO.
ionoptix2019-11-09T22:30:17-05:00Nickola, M. W., Wold, L. E., Colligan, P. B., Wang, G., Samson, W. K., & Ren, J. (2000). Hypertension, 36(4), 501-505
Late exercise training improves non-uniformity of transmural myocardial function in rats with ischaemic heart failure.
ionoptix2019-11-09T22:32:09-05:00Mou, Y. A., Reboul, C., Andre, L., Lacampagne, A., & Cazorla, O. (2008). Cardiovascular Research, 81(3), 555-564
Adenosine A2A and beta-adrenergic calcium transient and contractile responses in rat ventricular myocytes.
ionoptix2019-11-09T22:48:56-05:00Dobson, J. G., Shea, L. G., & Fenton, R. A. (2008). American Journal of Physiology-Heart and Circulatory Physiology, 295(6)