Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.
ionoptix2019-10-21T19:38:16-05:00Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Goldsworthy M, Hugill A, Freeman H, Horner E, Shimomura K, Bogani D, Pieles G, Mijat V, Arkell R, Bhattacharya S, Ashcroft FM, Cox RD Abstract: OBJECTIVES— To identify, map, clone, and functionally validate a novel mouse model for impaired glucose tolerance and insulin secretion. RESEARCH DESIGN AND METHODS— Haploinsufficiency of the insulin receptor and associated mild insulin [...]








