US: +1 617 696-7335 | EU: +31 317 728 104|info@ionoptix.com

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.

2019-10-21T19:38:16-05:00

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Goldsworthy M, Hugill A, Freeman H, Horner E, Shimomura K, Bogani D, Pieles G, Mijat V, Arkell R, Bhattacharya S, Ashcroft FM, Cox RD Abstract: OBJECTIVES— To identify, map, clone, and functionally validate a novel mouse model for impaired glucose tolerance and insulin secretion. RESEARCH DESIGN AND METHODS— Haploinsufficiency of the insulin receptor and associated mild insulin [...]

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.2019-10-21T19:38:16-05:00

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia.

2019-10-22T18:25:28-05:00

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia. Jernigan NL, Walker BR, Resta TC Abstract: Recent evidence supports a prominent role for Rho kinase (ROK)-mediated pulmonary vasoconstriction in the development and maintenance of chronic hypoxia (CH)-induced pulmonary hypertension. Endothelin (ET)-1 contributes to the pulmonary hypertensive response to CH and recent studies by our laboratory and others indicate that pulmonary vascular reactivity following [...]

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia.2019-10-22T18:25:28-05:00
Go to Top