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G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.

2019-11-09T22:16:04-05:00

Raake, P. W., Vinge, L. E., Gao, E., Boucher, M., Rengo, G., Chen, X., DeGeorge Jr., B.R., Matkovich, S., Houser, S.R., Most, P., Eckhart, A.D., Dornll, G.W., and Koch, W. J. (2008). Circulation Research, 103(4), 413-422

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.2019-11-09T22:16:04-05:00

The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension.

2019-10-22T19:56:51-05:00

The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Nieves-Cintrón M, Amberg GC, Navedo MF, Molkentin JD, Santana LF Abstract: Many excitable cells express L-type Ca2+ channels (LTCCs), which participate in physiological and pathophysiological processes ranging from memory, secretion, and contraction to epilepsy, heart failure, and hypertension. Clusters of LTCCs can operate in a PKCα-dependent, high open probability mode that generates sites of sustained Ca2+ [...]

The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension.2019-10-22T19:56:51-05:00

Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T.

2019-10-22T20:06:59-05:00

Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T. Lu XY, Chen L, Cai XL, Yang HT Abstract: Aims: Heat shock protein 27 (Hsp27) renders cardioprotection from ischaemia/reperfusion (I/R) injury, but little is known about its role in myofilaments. We proposed that increased expression of Hsp27 may improve post-ischaemic contractile dysfunction by preventing I/R-induced cardiac troponin I (cTnI) and troponin T [...]

Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T.2019-10-22T20:06:59-05:00

Sulfonylurea Receptor-Dependent and -Independent Pathways Mediate Vasodilation Induced by ATP-Sensitive K+ Channel Openers

2019-10-22T20:00:33-05:00

Sulfonylurea Receptor-Dependent and -Independent Pathways Mediate Vasodilation Induced by ATP-Sensitive K+ Channel Openers Adebowale Adebiyi, Elizabeth M. McNally and Jonathan H. Jaggar Abstract: ATP-sensitive K+ (KATP) channel openers are vasodilators that activate both plasma membrane and mitochondrial KATP channels. Here, we investigated the molecular mechanisms by which diazoxide and pinacidil induce vasodilation by studying diameter regulation of wild-type (SUR2+/+) and sulfonylurea receptor 2 deficient (SUR2-/-) mouse myogenic mesenteric arteries. Ryanodine [...]

Sulfonylurea Receptor-Dependent and -Independent Pathways Mediate Vasodilation Induced by ATP-Sensitive K+ Channel Openers2019-10-22T20:00:33-05:00

Cell volume control in phospholemman (PLM) knockout mice: do cardiac myocytes demonstrate a regulatory volume decrease and is this influenced by deletion of PLM?

2019-11-09T22:45:06-05:00

Bell, J. R., Lloyd, D., Curl, C. L., Delbridge, L. M., & Shattock, M. J. (2009). Experimental Physiology, 94(3), 330-343

Cell volume control in phospholemman (PLM) knockout mice: do cardiac myocytes demonstrate a regulatory volume decrease and is this influenced by deletion of PLM?2019-11-09T22:45:06-05:00
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