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Excitation-Contraction Coupling: Simultaneous Measures of Intracellular Calcium & Action Potentials

Patrick Schönleitner, PhD and Francisco Altamirano, PhD present their work involving simultaneous measurements of intracellular calcium, membrane voltage, and contractility of cardiomyocytes.

Key topics include:

  • From A to Z: How to perform simultaneous multi-parametric epifluorescence & contractility measurements in primary myocytes & hiPSC-CMs
  • The Good, The Bad, The Ugly: Opportunities, pitfalls, & limitation of simultaneous membrane potential & calcium measurements
  • Summarize differences between mouse & human cardiac action potentials
  • Identify pros & cons of hiPSC- derived cardiomyocytes to study cardiac action potentials & calcium handling

Access the webinar recording below.