IonOptix Video Tutorials: Operation of the C-Pace EM Culture Stimulator
ionoptix2022-11-21T13:20:08-05:00A video tutorial demonstrating operation of the IonOptix C-Pace EM culture stimulator.
IonOptix Video Tutorials: Murine Cardiomyocyte Isolation
ionoptix2022-08-09T18:06:53-05:00A video tutorial highlighting murine cardiomyocyte isolation protocol and techniques.
C-Pace EM Brochure
ISC Webmaster2020-12-01T17:22:38-05:00Go back to RESOURCES C-Pace EM Brochure Download
C-Pace EM Manual
ISC Webmaster2020-11-23T14:54:24-05:00Go back to RESOURCES C-Pace EM Manual Download
Benefits Of Chronic Pacing Of Cells In Culture
ISC Webmaster2019-10-22T17:51:23-05:00Chronic electrical stimulation has been shown to prevent the dedifferentiation of myocytes that occurs in long term culture...
Applications For The C-Pace System
ISC Webmaster2019-10-22T17:42:33-05:005 years of the C-Pace: a short review Cardiac tissue * Skeletal muscle * Stem cells * Cell-lines * Cardiogenic Fibroblasts * Neuronal fibroblasts * Osteoblasts It has been more than 5 years …
Culture Pacing
ISC Webmaster2019-11-10T19:56:46-05:00Engineered skeletal muscle from electrically stimulated myoblast cells Check out this video from researchers at the Department of Biomedical Engineering, Eindhoven University of Technology.
Rapid electrical stimulation induces early activation of kinase signal transduction pathways and apoptosis in adult rat ventricular myocytes.
ionoptix2019-10-22T17:43:24-05:00Rapid electrical stimulation induces early activation of kinase signal transduction pathways and apoptosis in adult rat ventricular myocytes. Kuramochi Y1, Guo X, Sawyer DB, Lim CC Abstract: Chronic tachycardia in patients and rapid pacing in animal models induce myocardial dysfunction and initiate a cascade of compensatory adaptations that are ultimately unsustainable, leading to ventricular enlargement and failure. The molecular pathogenesis during the early stages of tachycardia-induced cardiomyopathy, however, remains unclear. [...]
Induction of heat shock response protects the heart against atrial fibrillation.
ionoptix2019-10-22T17:44:44-05:00Induction of heat shock response protects the heart against atrial fibrillation. Brundel BJ, Shiroshita-Takeshita A, Qi X, Yeh YH, Chartier D, van Gelder IC, Henning RH, Kampinga HH, Nattel S Abstract: There is evidence suggesting that heat shock proteins (HSPs) may protect against clinical atrial fibrillation (AF). We evaluated the effect of HSP induction in an in vitro atrial cell line (HL-1) model of tachycardia remodeling and in tachypaced isolated [...]