Hancock EN, Palmer BM, Caporizzo MA (2024). Microtubule destabilization with colchicine increases the work output of myocardial slices. J Mol Cell Cardiol Plus. 2024 Mar;7:100066. doi: 10.1016/j.jmccpl.2024.100066.
Preparing Excitable Cardiac Papillary Muscle and Cardiac Slices for Functional Analyses (2022)
ionoptix2026-05-14T08:46:12-05:00Palmer BM and Bell SP (2022) Preparing Excitable Cardiac Papillary Muscle and Cardiac Slices for Functional Analyses. Front. Physiol. 13:817205. doi: 10.3389/fphys.2022.817205
Sarcomere integrated biosensor detects myofilament-activating ligands in real time during twitch contractions in live cardiac muscle (2020)
ionoptix2026-05-15T18:02:48-05:00Vetter AD, Martin AA, Thompson BR, Thomas DD, Metzger JM (2020). Sarcomere integrated biosensor detects myofilament-activating ligands in real time during twitch contractions in live cardiac muscle. J Mol Cell Cardiol. 2020 Oct;147:49-61. doi: 10.1016/j.yjmcc.2020.07.012.
FSI800 User Manual
ionoptix2026-06-03T15:57:09-05:00Hardware manual for the IonOptix Fluorescence System Interface.
StimSwitch User Manual
ionoptix2026-04-22T17:11:54-05:00Hardware manual for the IonOptix StimSwitch.
MyoClamp System Handout
ionoptix2026-02-19T13:29:54-05:00Handout describing MyoClamp System features.
Modified Langendorff-free Cardiomyocyte Isolation
ionoptix2025-08-18T18:04:20-05:00This protocol describes the isolation of primary adult mouse cardiomyocytes using sequential calcium depletion, enzymatic digestion, and gradual calcium reintroduction. The approach is adapted from the method of Matthew Ackers-Johnson et al.
MyoClamp System User’s Guide
ionoptix2026-04-22T17:13:08-05:00User's guide for the MyoClamp System for functional data from intact muscle tissue.
KoForce Force Calibration Worksheet
ionoptix2026-02-19T13:31:32-05:00KoForce force calibration worksheet
Work Loop Power Analysis
ionoptix2026-02-06T15:19:10-05:00Work Loop Power Analysis: Mechanical work in myocardial slices
AP Measurements: iPSC- vs primary cardiomyocytes
ionoptix2025-05-14T18:46:59-05:00Action Potential Measurements in iPSC-derived and Primary Cardiomyocytes
CytoCypher MultiCell User’s Guide
ionoptix2026-05-11T16:20:22-05:00User's guide for the CytoCypher MultiCell System.
Best Practices – Measuring Force, Resting Sarcomere Length, and Calcium in Cardiac Slices
ionoptix2026-02-04T12:46:21-05:00In this virtual demo, Drs. Adam Veteto and Hanan Qasim show how to successfully acquire force, resting sarcomere length, and calcium data from cardiac slices, including tips and best practices.
Understanding Advanced Cardiac Tissue Slice Applications
ionoptix2026-02-19T13:32:59-05:00Drs. Bradley Palmer, Matthew Caporizzo, and Benjamin Lee share how the IonOptix Cardiac Slice System can be used to complement and improve upon traditional cardiac investigations.
Calcium Indicator Dye Loading in Cardiac Slices
ionoptix2026-02-04T12:46:43-05:00Calcium Indicator Dye Loading in Cardiac Slices
CytoSolver FAQs: CytoMotion Contractility Module
ionoptix2023-12-04T18:54:09-05:00CytoSolver FAQs: CytoMotion Contractility Module