Dr. Joe Soughayer and Dr. Adam Veteto provide an in-depth overview of excitation-contraction (E-C) coupling in cardiomyocytes and the tools to characterize this.
Excitation-Contraction Coupling: Simultaneous Measures of Intracellular Calcium & Action Potentials
ionoptix2022-09-14T17:41:27-05:00Patrick Schönleitner, PhD and Francisco Altamirano, PhD present their work involving simultaneous measurements of intracellular calcium, membrane voltage, and contractility of cardiomyocytes.
Measuring iPSC-CM Calcium & Contractility
ionoptix2023-01-31T14:41:13-05:00Measuring hiPSC-CM Ca & Contractility
iPSC-derived Cardiomyocyte Contractility Acquisition and Analysis Demo
ionoptix2022-08-09T17:46:40-05:00Understand how to acquire and analyze contractility data from iPSC-derived cardiomyocytes.
A How-To Demonstration of Higher Throughput Excitation-Contraction Coupling Investigations
ionoptix2021-08-18T16:41:11-05:00From myocyte isolation to data acquisition, analysis, and post-analysis plotting, Dr. Michiel Helmes and Dr. Diederik Kuster demonstrate best practices and new techniques in high-content, higher throughput investigations of excitation-contraction coupling in isolated cardiomyocytes.
Simultaneous Action Potential, Calcium, and Contractility Case Study
ionoptix2021-01-12T11:42:41-05:00Combined OAP, Ca, and Cont measurements in adult cardiomyocytes
IonOptix Video Tutorials: Murine Cardiomyocyte Isolation
ionoptix2022-08-09T18:06:53-05:00A video tutorial highlighting murine cardiomyocyte isolation protocol and techniques.
IonOptix Video Tutorials: IonWizard Experiment Design
ionoptix2020-08-03T20:08:16-05:00A video tutorial highlighting experiment design in IonWizard.
IonOptix Video Tutorials: Calcium & Contractility System Acquisition Quick Start
ionoptix2020-06-24T15:23:20-05:00A video tutorial highlighting best practices for data acquisition of calcium and contractility data.
IonOptix Video Tutorials: CytoSolver Batch Analysis
ionoptix2020-05-12T11:11:36-05:00A simple video tutorial highlighting analysis of calcium and contractility data using IonWizard.
IonOptix Video Tutorials: Analyzing Unmarked Events
ionoptix2020-04-28T11:26:46-05:00A simple video tutorial highlighting analysis of calcium and contractility data using IonWizard.
IonOptix Video Tutorials: IonWizard Data Analysis
ionoptix2020-04-17T10:58:21-05:00A simple video tutorial highlighting analysis of calcium and contractility data using IonWizard.
Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription.
ISC Webmaster2019-11-09T22:14:04-05:00Fang, C. X., Dong, F., Thomas, D. P., Ma, H., He, L., & Ren, J. (2008). American Journal of Physiology-Heart and Circulatory Physiology, 295(3)
InsideAnswers: Techniques and Best Practices for Cardiomyocyte Isolation
ISC Webmaster2019-11-11T16:27:21-05:00In this Q&A video series, experts address your best questions and greatest challenges with regards to cardiomyocyte isolation, purification, culture and analysis.
Measuring Force in Single Heart Cells
ISC editor2019-12-06T14:34:29-05:00New technology now provides investigators the ability to reliably attach myocytes, mechanically stretch them, make direct force measurements and control cell length intelligently. This webinar reviews best-practices and techniques for attaching, stretching, and studying isolated cells.
Measuring Work in Single Isolated Cardiomyocytes: Replicating the Cardiac Cycle
ISC editor2019-12-06T14:35:29-05:00A special webinar for basic cardiovascular researchers interested in a novel technique for measuring work output and replicating the four phases of the cardiac cycle at the single cell level.
Techniques and Best Practices for Cardiomyocyte Isolation
ISC editor2019-12-06T14:33:27-05:00Ronglih Liao and Davor Pavlovic discuss techniques for isolating myocytes using both traditional and Langendorff-free methodologies.
High Throughput Investigation of EC Coupling in Isolated Cardiac Myocytes
Andy Henton2019-10-03T07:46:45-05:00Michiel Helmes, PhD presents new technology and methodology for fast data acquisition and functional analysis of cardiac myocytes, leading to better lab practices and data interpretation.