The cardiac work cycle consists of four well-defined isometric and isotonic phases. The IonOptix MultiClamp software enables fast feedback control of pre- and after-load force levels. Together with the IonOptix MyoStretcher OptiForce force transducer and fast piezo motor, we can modulate the force development by rapidly changing the length of the myocyte in response to changing force load. By clamping the diastolic and systolic force levels (pre- and after-load), we can mimic the cardiac cycle, enabling work measurements in single, isolated cardiomyocytes.


  • Mimic cardiac cycle in single cells

  • Fast feedback clamp of pre- and after-load forces

  • Programmable control of pre- and after-load levels

Note: This product is intended for research purposes only. It is not certified for clinical applications (including diagnostic purposes). Use of this product in uncertified applications is in violation of FDA regulations.

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